The Jubilee Line will shut for 30 days over the next two years while £40m of repair work is carried out to the tunnel walls.
Transport for London said the cast iron tunnel linings are being eroded by acidic water.
Services will be halted between Finchley Road and Waterloo in central London during a series of staged shutdowns to carry-out the repairs.
The first shutdown will be Sunday June 16.
The acidic water comes from naturally occurring ground water seeping in from surrounding soil.
TfL engineers are concerned about the state of more than 90 yards of the southbound tunnel between Baker Street and Bond Street.
The Standard reported that a notice issued to staff by Tube Lines, the LU subsidiary company responsible for the Jubilee line, confirms the tunnel has been “affected by acid ingress”.
Sections of tunnel linings will now have to be replaced.
Stuart Harvey, LU programme director for the Jubilee, Northern and Piccadilly lines, said: “All railways require maintenance and we will soon be carrying out work on the tunnel lining on a section of the Jubilee line.
“I apologise to customers for the disruption. We’ll be keeping the impact to a minimum by spreading the work out.”